LEISTUNGSKATALOG
| Service | Details |
|---|---|
| DNA Extraction | accepted starting material: blood, FFPE slides, dry blood spots, bucal swabs, saliva. |
| RNA Extraction |
Sample QC and library QC is included in the project price. In case samples are being resubmitted, the following charges will apply.
| Service | Details |
|---|---|
| Qubit/Fluoroskan | |
| TapeStation | |
| Library Cleanup und QC | in case of pre-made libraries |
| Service | Details |
|---|---|
| WGS / WES | |
| Standard Whole-Genome Sequencing | germline (30x coverage) or somatic (50x coverage) |
| PCR-free Whole-Genome Sequencing | germline (30x coverage) or somatic (50x coverage) |
| Whole-Exome Sequencing | germline (20x coverage) or somatic (100x coverage) |
| Target enrichment | |
| PathoNext Gene Panel for solid and hematologic tumors | |
| AVENIO Gene Panel (Roche) | batch of 2 or 8 samples |
| AmoyDx® HRD Focus Panel | |
| Archer® FusionPlex® Lung v2 Panel | |
| LymphoTrack®Dx Assay | |
| RNA-Seq | |
| Metagenomics | |
| Shotgun sequencing | 3GB/sample |
| Service | Details |
|---|---|
| MiSeq | |
| MiSeq 2x150bp | Reagent Kit v2 |
| MiSeq 2x300bp | Reagent Kit v3 |
| NextSeq | |
| NextSeq 2x150 bp (MidOutput) | |
| NextSeq 2x150 bp (HighOutput) | |
| NovaSeq | |
| NovaSeq SP 2x150bp | |
| NovaSeq SP 2x250bp | |
| NovaSeq S1 2x150bp | |
| NovaSeq S2 2x150bp | |
| NovaSeq S4 2x150bp | per flowcell or lane |
| NovaSeq 2x150bp sequencing | assuming the samples will be multiplexed on an SP flowcell together with other projects |
Data QC is included in the project price.
| Service | Details |
|---|---|
| DNA Analysis | |
| Germline Variant Calling - small panel (<5MB) | including trimming, mapping to reference genome, and variant calling |
| Germline Variant Calling - medium panel (<30MB) | including trimming, mapping to reference genome, and variant calling |
| Germline Variant Calling - WGS/WES (>30MB) | including trimming, mapping to reference genome, and variant calling |
| Somatic Variant Calling - small panel (<5MB) | including trimming, mapping to reference genome, and variant calling |
| Somatic Variant Calling - medium panel (<30MB) | including trimming, mapping to reference genome, and variant calling |
| Somatic Variant Calling - WGS/WES (>30MB) | including trimming, mapping to reference genome, and variant calling |
| Structural Variant Analysis | add-on service to variant calling |
| Variant Annotation and Interpretation | |
| RNA Analysen | |
| Differential Gene Expression Analysis | including trimming, mapping to reference, and quantification of gene expression |
| Detection of fusion genes | including trimming, mapping to reference and detection of fusion genes |
| RNA Variant Calling | including trimming, mapping to reference genome, and variant calling |
| Metagenomics | |
| Taxonomic classification | |
| Estimation of microbial diversity | add-on service |
| Analysis of antimicrobial resistance genes and markers | |
| Panel Design for Target Enrichment | in cooperation with our partners |